Book direct
and save up to 10%
compared to Booking.com
Check rooms and rates
From129US$ /night
Check-in
21Aug2025Select date
Check-out
22Aug2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

110 Miller Street, Winston-Salem, North Carolina, United States, 27103

Holiday Inn Express Winston-Salem Medical Ctr Area - Business-friendly hotel with free breakfast near Wake Forest University

Located in downtown Winston-Salem, this hotel is a short walk from the Greensboro Coliseum and Wake Forest University. It features an outdoor seasonal pool, a 24-hour fitness center, and a business center. Guests receive a free hot breakfast buffet. The property includes a 24-hour front desk, free Wi-Fi, and an on-site convenience store. Nearby attractions include Hanes Mall, Old Salem, and Reynolda House Museum of American Art.

Additional perks of the hotel

Free Express Start Breakfast with hot buffet options

Outdoor seasonal pool open from May 31 to September 6

24-hour gym and business center

On-site convenience store with snacks and drinks

Complimentary self-parking

Staff praised for excellent service, particularly bartender Sarah

Guest rooms

Rooms include a private bathroom with a bath or shower, a 32-inch flat-screen TV with cable channels, and free Wi-Fi. Each room has a microwave, small refrigerator, and coffee maker. Bedside outlets, plush duvets, and pillow options ensure comfort. Some rooms feature air conditioning, heating, a desk, and a telephone.

Other conveniences

Iron and ironing board in every room

Free local calls and voicemail

Hair dryer and separate vanity area

Complimentary coffee and tea supplies

Wheelchair-accessible rooms available

Connecting rooms upon request

View all

Choose Your Room

Our listed hotels offer a variety of room types—double rooms, family suites, or deluxe options—all with features like breakfast, flexible cancellation policies, and exclusive deals.
Standard King Room
Max:
2 persons
35 sq. feet 
Bed options:
1 King-size bed
Shower
Heating
Check Prices
Double Room Two Double Beds
Max:
2 persons
35 sq. feet 
Bed options:
2 Double beds
Shower
Heating
Check Prices
Standard Room Two Queen Beds
Max:
4 persons
35 sq. feet 
Bed options:
2 King Size Beds
Shower
Heating
Check Prices
Show all roomsLess

Room Rates & Availability Tracker

Find Deals for Your Travel Dates

Transportation Tips

Transportation Options

City Centre
Winston-Salem 1.7 mi
Airports
Piedmont Triad (GSO) 22.4 mi
Mota Lava (mtv) 60.9 mi

Amenities

Thoughtful hotel amenities for a comfortable stay

General

  • No smoking on site
  • Free Wi-Fi
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Hiking
  • Horseback riding
  • Bowling

Services

  • Laundry
  • Shops/Commercial services

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Seasonal outdoor pool
  • Live entertainment

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities

Bathroom

  • Free toiletries

Media

  • AM/FM alarm clock
Show more

Hotel Location

110 Miller Street, Winston-Salem, North Carolina, United States, 27103
Map view
110 Miller Street, Winston-Salem, North Carolina, United States, 27103
Nearby
Mall
Thruway Shopping Center
1900 ft
Park
Miller Park
1900 ft
Hospital
Wake Forest Baptist Health
1600 ft
Restaurants
Mayberry Ice Cream Restaurants
1000 ft
50 Miller St
Thai Sawatdee
1000 ft
2281 Cloverdale Ave
Cloverdale Kitchen
1000 ft
2251 Cloverdale Ave
Cagneys' Restaurant Incorporated
1100 ft
2201 Cloverdale Ave
Kowloon Chinese Restaurant
1300 ft
2255 Cloverdale Ave Cloverdale Plaza
Wendy's
1300 ft
2218 Cloverdale Avenue
Moe's Southwest Grill
3200 ft
206 S Stratford Rd
Jimmy John's
3600 ft
237 S Stratford Rd
Krispy Kreme Doughnuts
3700 ft
259 S Stratford Rd

Guest Reviews & Ratings

What Guests Are Saying?
Guest reviews
5.0/10
based on 3 reviews
8.8
8.8/10 based on 279 reviews
Sarah
United States, April  2024
7.6/10

I was pleasantly surprised by the hotel - the location is perfect near restaurants and Wake Forest Baptist Hospital, making it ideal for those needing easy access to the medical center. The service was friendly, and the staff was accommodating to my specific needs. However, the rooms had a few issues with cleanliness that were off-putting, and the breakfast could use some improvement in terms of variety and presentation.

Rooms
6.0
The room had its drawbacks starting with an unmade bed and trash, but I appreciated the effort to rectify the situation. The double beds were a step down from what I had at the previous hotel.
Service
8.0
The service was friendly and accommodating, particularly for those visiting the university or medical center. The staff took the time to assist and find discounts for guests like me, adding a personal touch to the experience.
Location
9.0
The location was key for my stay, being conveniently close to Wake Forest Baptist Hospital and other nearby stores and restaurants like Panera. Perfect for those needing easy access to the medical center.
Dining
7.0
The breakfast started early, which was convenient, but the use of plastic plates and cutlery was a downside. Despite serving a variety of food and drinks, the presentation could be improved.
Facilities
8.0
The hotels' facilities, including laundry services and shops, were useful additions to my stay, adding convenience to the overall experience.
clean
unmade bed
William
United States, January  2024
7.8/10

My stay at the hotel was pleasant overall. The rooms were decent, but the air conditioning was blowing warm air instead of cooling. The service was friendly and accommodating, which made my experience more enjoyable. The location was convenient, with easy access to the Wakeforest Baptist hospital and not far from downtown Winston-Salem. The dining experience was good, although I had to wait a bit for different items to be ready. The facilities met my needs during my stay.

Rooms
7.0
The rooms were decent, although the air conditioning was blowing warm air instead of cooling.
Service
8.0
The service was friendly and accommodating.
Location
9.0
The location was convenient, with easy access to the Wakeforest Baptist hospital and not far from downtown Winston-Salem.
Dining
7.0
The dining experience was good, but I had to wait for different items to be ready.
Facilities
8.0
The facilities met my needs during my stay.
Rob
United States, May  2023
6.0/10

The hotel rooms were decent but fell short of expectations compared to a previous stay elsewhere. They had a noticeable smell of smoke and rotten milk, giving an overall old and in need of deep cleaning vibe. On a positive note, the hotel is located conveniently for shopping and dining, although some plumbing issues were evident.

Rooms
5.0
The room smelled like smoke and rotten milk, needing a deep cleaning, and had a dated feel.
Service
7.0
The staff was somewhat inattentive, but overall friendly and accommodating.
Location
6.0
The location was convenient for shopping and dining, although there were some plumbing issues affecting it.
Dining
7.0
Limited dining choices affected the overall experience.
Facilities
6.0
The facilities were clean and well-organized, however lacking in variety and appeal.
Unlock Early Booking Discounts
Grab Your Special Rates Today!
Check Rates

Next best alternative

Consider them for your next trip.
Check-in
21Aug2025Select date
Check-out
22Aug2025Select date
Rooms and Guests2 Guests, 1 Room